300 mg DMG per serving. Other ingredients: W ater. Dosage: 1 ml dropper twice daily. 60 doses per bottle. Refrigerate upon opening. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Dimethylglycine and Autism Ranking: Dimethylglycine (also known as DMG) is a derivative of the amino acid glycine. It is found naturally in plant and animal cells.
A third clinical trial conducted more recently, involving 84 subjects, found that DMG decreased problematic behaviours in those with autism (Edelson, 2002). There is also anecdotal evidence from parents, medical professionals, and caretakers suggesting that DMG does provide benefits for some children with autism (Autism Research Institute, 2011). Dimethylglycine (DMG) for Autism, Asperger’s Syndrome. Of 5,807 Autism Research Institute ratings provided by parents of autistic children, 42% saw improvements with DMG supplementation, 51% saw no change, and 8% said symptoms worsened (total is higher than 100% because percentages are rounded up to the nearest whole). The use of DMG to treat autism is controversial, and current research shows mixed results. Two double-blind, placebo-controlled studies did not demonstrate differences between DMG and a placebo.1 DMG is reportedly nontoxic with no significant adverse effects. A German investigator, V. Bonisch, reported in 1968 that 12 of 16 children with autism had shown considerable behavioral improvement when given high dosage levels (100 mg to 600 mg per day) of vitamin B6.
Dimethylglycine, also known as DMG, is a natural substance found in both plant and animal cells, and is derived from the amino acid glycine (see reference 1 under Clinical Summary para 1). As a supplement, it is purported to offer a number of health benefits, from enhancing physical performance to improving behavior in children with autism and attention deficit disorder. However, the evidence to support these claims is lacking, according to the Memorial Sloan Kettering Cancer Center (see reference 1 under Mechanism of Action).
How DMG Works
The body produces DMG in the cells by breaking down choline (see reference 1 under Clinical Summary). In the body, it acts as an antioxidant and improves oxygenation of the cells (see reference 1 under Clinical Summary). The thought is that taking DMG as a supplement may further enhance oxygenation, which improves athletic performance (see reference 1 under Clinical Summary). It is also thought to act as a neurological stimulator, which is why it has gained popularity in the autism community (see reference 1 under Clinical Summary). According to an October 2009 review article on the use of complementary medicine in autism published in 'Child and Adolescent Psychiatric Clinics,' the two clinical trials testing the use of DMG on children with autism showed no positive effect or improvement in behavior (see reference 2 under DMG).
Dmg Autism Dosage Chart
Safety Concerns
Dmg Autism Dosage Side Effects
DMG is considered a safe and non-toxic substance, according to MSKCC (see reference 1 under Clinical Summary). If you're supplementing your diet with DMG, be sure to inform your doctor to monitor for any potential side effects or interactions. Additionally, while it's safe to take DMG, do not rely on it as a cure or treatment for any illness.